The prestigious accolade comes from the company’s latest book entitled 1,000 Ultimate Sights.
Nestled in Enniskerry in the Wicklow Mountains, Powerscourt Estate originally held a castle dating from the 12th century which was remodelled as a magnificent Palladian mansion in the 18th century.
It was renovated in 1996 and now features a beautifully restored Georgian ballroom, garden rooms, an audio visual presentation telling the history of the house, speciality shops and a terrace café.
The house is set in 1,000 acres of gorgeous grounds which include 47 acres of landscaped gardens.
Features include Italian and Japanese gardens, statues and ornamental lakes, woodland walks, and over 200 variations of trees and shrubs.
The estate also boasts the highest waterfall in Ireland and two championship golf courses.
Powerscourt was one of only four sights from European countries to make the 1,000 Ultimate Sights list and the only entry from Ireland.
The other European entries were Castle Howard in England, Villa d’Este in Italy and Chateau de Chambord in France.
Sarah Slazenger, General Manager of Powerscourt Estate said: "Everyone should see the great sights of the world and the Lonely Planet has done the traveller a great service by including Powerscourt in the top ten Houses and Mansions Worldwide."
Powerscourt Estate welcomes over 500,000 visitors a year and has served as a film location for over 25 films and TV series including The Count of Monte Cristo, King Arthur, Ella Enchanted, The Tudors and Camelot.
Open all year round, Powerscourt Estate is located only 20 minutes from Dublin.